ICTUImperial Clinical Trials Unit

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Use of image-directed tumour biopsies to examine pharmacodynamic changes

Prof Hanni Gabra has demonstrated the feasibility of collecting image-directed tumour biopsies at presentation, during treatment and at relapse of certain cancers and used this to examine pharmacodynamic changes and stratification biomarkers in patients enrolled in specific clinical trials and studies. We have used such approaches to investigate predictive biomarkers and tumour stem cells.