ICTUImperial Clinical Trials Unit

Welcome to Imperial Clinical Trials Unit (ICTU)

This website is intended for commercial trial sponsors engaged in the area of pharmaceuticals, medical devices or diagnostic devices

Mental Health

ICTU is collaborating with Dr Paul Ramchandani to coordinate the “Preventing enduring behavioural problems in young children through early psychological intervention: Healthy Start, Happy Start” study

The Healthy Start, Happy Start trial is funded by the NIHR HTA programme and aims to recruit 300 families with infants aged 12 to 36 months.

The aim of the trial is to evaluate the effectiveness and cost-effectiveness of a video-feedback intervention to prevent enduring behavioural problems in young children. The trial is currently in the set-up phase.

The Neuroepidemiology and Ageing (NEA) Research Unit has huge experience in the pre-syptomatic phase of neurodegeneration, with particular interest in prevention, i.e. very early Alzheimer’s disease and dementia. It is currently running an interventional and an observational study in Alzheimer’s Disease which draw on some very strong capability in PET imaging). The NEA Research unit also has unique access to the CHARIOT register of 20,000 people with consent to be approached for trials in this area. This register excludes patients diagnosed with dementia but includes some patients with early cognitive decline.

In partnership with Imanova, a specialised on-campus imaging facility, it's also possible to also integrate fMRI and PET scanning into neurological study design. This enables Sponsors to investigate receptor occupancy of compounds and conduct highly informed dose-finding studies.