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UK HVC Spoke 003

Trial Details

A Phase I clinical trial investigating immunisation strategies using DNA, MVA and CN54rgp140 adjuvanted with GLA-AF to maximise antibody responses

Design and Objective

Design: A randomised Phase I, two centre study

Key inclusion criteria

1. Man or woman aged between 18 and 45 years on the day of screening 2. Available for follow-up for the duration of the study (up to ~10 months from enrolment) 3. At low risk of HIV 4. Willing to undergo an HIV test and a genital infection screen if indicated by sexual history 5. Effective contraception 6. Agree to abstain from blood donation

Study Disclaimer Statement